Selected Publications

*See CV for current list of publications

Principles and procedures for handling out-of-domain and indeterminate results as part of ICH M7 recommended (Q)SAR analyses. View
Amberg A, Andaya R, Anger L, Barber C, Beilke L, et al., (2019). Regulatory Toxicology and Pharmacol., 102:53-64.

In silico toxicology protocols.
Myatt GJ, Ahlberg A, Akahori Y, Allen D, Amberg A, Anger LT, Aptula A, Auerbach S, Beilke L, et al. (2018). Reg Tox and Pharmacol., 96:1-17. View

In Silico Tools and their Application. Chapter to be published in Comprehensive Medicinal Chemistry III: ADME and Toxicology: A Comprehensive Overview of the Current Status and Application of Predictive ADMET
(Editor: Alan G.E. Wilson).  
Beilke LD, Cross KP, Myatt GJ (TBD).


CAR-Mediated changes in bile acid composition contributes to hepatoprotection from LCA-induced liver injury in mice.
Beilke LD, Aleksunes L, Holland R, Besselsen D, Beger R, Cherrington N. Drug Metabolism and Disposition. 2009, 37(5):1035-45. View

Decreased apoptosis during CAR-mediated hepatoprotection against lithocholic acid-induced liver injury in mice. (2009)
Beilke LD, Aleksunes L, Olson E, Besselsen D, Klaassen C, Dvorak K, Cherrington N. Toxicology Letters. 188(1):38-44. View

Minimal role of hepatic transporters in the hepatoprotection against LCA-induced intrahepatic cholestasis.
Beilke LD, Besselsen D, Chen Q, Kulkarni S, Slitt A, Cherrington N. Toxicol Sci., 2008, 102(1):196-204.
View

Lack of respiratory and contact sensitizing potential of the intranasal antiviral drug candidate rupintrivir(AG7088): a weight-of-the-evidence evaluation.
Burns-Naas LA1, Lee C, Evering W, Ahern L, Webber S, Zorbas M. J Immunotoxicol. 2005 Jul 1;2(3):123-39.

Genetic toxicology in silico protocol.
Hasselgren C, Ahlberg E, Akahori Y, Amberg A, Anger L, Atienzar F, Auerbach S, Beilke L, et al. (2019). Reg Tox and Pharmacol., in press. View

Extending (Q)SARs to incorporate proprietary knowledge for regulatory purposes: A case study using aromatic amine mutagenicity.
Ahlberg A, Amberg A, Beilke L, Bower D, Cross K, Custer L, et al. (2016). Reg Tox and Pharmacol., 77:1-12. View

Principles and procedures for implementation of ICH M7 recommended (Q)SAR analyses. 
Amberg, A, Beilke, L, Bercu J, Bower D, Brigo A, et al. (2016). Regulatory Toxicology and Pharmacol., 77:13-24. View 


Thiotepa. In: Wexler, P. (Ed.), Encyclopedia of Toxicology, 3rd edition vol 4. Elsevier Inc., Academic Press, pp. 551–552.
Beilke, LD, 2014.

American Academy of Clinical Toxicology. In: Wexler, P. (Ed.), Encyclopedia of Toxicology, 3rd edition vol 1. Elsevier Inc., Academic Press, pp. 170–171. Beilke, LD, 2014.